Tuesday, July 8, 2025
  • Home
  • National
  • International
  • Movies
  • Technology
  • Business
  • Fitness
  • Lifestyle
  • Punjab
  • Contact us
No Result
View All Result
No Result
View All Result
Home National

Rajnath Singh releases DRDO’s anti-COVID drug, know about 2-deoxy-D-glucose | India News

by author
May 17, 2021
in National
0
Rajnath Singh releases DRDO’s anti-COVID drug, know about 2-deoxy-D-glucose | India News
0
SHARES
17
VIEWS
Share on FacebookShare on Twitter


New Delhi: Defence Minister Rajnath Singh on Monday (May 17, 2021) released the first batch of the anti-COVID-19 drug 2-deoxy-D-glucose (2-DG) to strengthen India’s fight against the coronavirus. Union Health Minister Harsh Vardhan and AIIMS Delhi Director Dr Randeep Guleria were also present during the release.

Over 10,000 doses of the 2-DG drug, which comes in powder form and is taken orally by dissolving it in water, were launched.

The first batch of anti Covid-19 drug, 2-DG is being released. Sharing my thoughts on the occasion. https://t.co/1dAM91jttg

— Rajnath Singh (@rajnathsingh) May 17, 2021

The anti-COVID-19 therapeutic application of the drug 2-deoxy-D-glucose has been developed by the Institute of Nuclear Medicine and Allied Sciences (INMAS), a lab of Defence Research and Development Organisation (DRDO), in collaboration with Dr Reddy’s Laboratories (DRL), Hyderabad. 

It was approved for emergency use as an adjunct therapy in moderate to severe COVID-19 patients by the Drugs Controller General of India (DCGI) on May 1.

Clinical trial results have shown that this molecule helps in faster recovery of hospitalised patients and reduces supplemental oxygen dependence. A higher proportion of patients treated with 2-DG showed RT-PCR negative conversion in COVID patients. The drug will be of immense benefit to the people suffering from COVID-19.

Back in April 2020, during the first wave of the coronavirus in India, the INMAS-DRDO scientists conducted laboratory experiments with the help of the Centre for Cellular and Molecular Biology (CCMB), Hyderabad and found that this molecule works effectively against the SARS-CoV-2 virus and inhibits the viral growth. Based on these results, the DCGI Central Drugs Standard Control Organization (CDSCO) permitted Phase-II clinical trial of 2-DG in COVID-19 patients in May 2020.
DRDO'S anti-COVID-19 drug 2-deoxy-D-glucose (2-DG)

The DRDO, along with its industry partner DRL, Hyderabad, started the clinical trials to test the safety and efficacy of the drug in coronavirus patients and during Phase-II trials (including dose ranging) conducted during May to October 2020, the drug was found to be safe in COVID-19 patients and showed significant improvement in their recovery. 

This is to be noted that Phase IIa was conducted in six hospitals and Phase IIb (dose ranging) clinical trial was conducted at 11 hospitals all over the country. Phase-II trial was conducted on 110 patients.

According to the Ministry of Defence, in efficacy trends, the patients treated with the 2-DG drug showed faster symptomatic cure than Standard of Care (SoC) on various endpoints. A significantly favourable trend (2.5 days difference) was seen in terms of the median time to achieving normalisation of specific vital signs parameters when compared to SoC.

DRDO'S anti-COVID-19 drug 2-deoxy-D-glucose (2-DG)

Based on successful results, DCGI further permitted the Phase-III clinical trials in November 2020 which was conducted on 220 patients between December 2020 to March 2021 at 27 COVID hospitals in Delhi, Uttar Pradesh, West Bengal, Gujarat, Rajasthan, Maharashtra, Andhra Pradesh, Telangana, Karnataka and Tamil Nadu. 

Subsequently, the detailed data of the phase-III clinical trial was presented to DCGI. 

In the 2-DG arm, a significantly higher proportion of patients improved symptomatically and became free from supplemental oxygen dependence (42% vs 31%) by Day-3 in comparison to SoC, indicating an early relief from Oxygen therapy/dependence.

A similar trend was observed in patients aged more than 65 years. 

DRDO'S anti-COVID-19 drug 2-deoxy-D-glucose (2-DG)

“Being a generic molecule and analogue of glucose, it can be easily produced and made available in plenty in the country,” the Ministry of Defence stated on May 8. 

The drug accumulates in the virus infected cells and prevents virus growth by stopping viral synthesis and energy production. Its selective accumulation in virally infected cells makes this drug unique. 

2-deoxy-D-glucose also reduces the hospital stay of COVID-19 patients and is likely to play a key role in India’s fight against the second wave of COVID-19. 
 





Source link

Related posts

RTI Reveals Spy Suspect Jyoti Malhotra Was Kerala Govts State Guest; Custody Extended Till July 21

RTI Reveals Spy Suspect Jyoti Malhotra Was Kerala Govts State Guest; Custody Extended Till July 21

July 8, 2025
UK F-35B Jet Under Repair In Kerala, UK Grateful To India For Support

UK F-35B Jet Under Repair In Kerala, UK Grateful To India For Support

July 7, 2025
Tags: indian newsnational news
Previous Post

UN chief remarks Israel-Palestine conflict 'utterly appalling' as death toll reaches 192 in Gaza, 10 in Israel | World News

Next Post

Is Cyclone Tauktae an indication towards a new trend for Arabian Sea?

Related Posts

RTI Reveals Spy Suspect Jyoti Malhotra Was Kerala Govts State Guest; Custody Extended Till July 21
National

RTI Reveals Spy Suspect Jyoti Malhotra Was Kerala Govts State Guest; Custody Extended Till July 21

July 8, 2025
UK F-35B Jet Under Repair In Kerala, UK Grateful To India For Support
National

UK F-35B Jet Under Repair In Kerala, UK Grateful To India For Support

July 7, 2025
BRICS Leaders Strongly Condemn Pahalgam Terror Attack, Reject ‘Double Standards’ In Countering Terrorism | India News
National

BRICS Leaders Strongly Condemn Pahalgam Terror Attack, Reject ‘Double Standards’ In Countering Terrorism | India News

July 7, 2025
Amarnath Yatra 2025: Over 26,800 Devotees Complete Journey In 2 Days, Fresh Batch Of 6,979 Leaves For Kashmir | India News
National

Amarnath Yatra 2025: Over 26,800 Devotees Complete Journey In 2 Days, Fresh Batch Of 6,979 Leaves For Kashmir | India News

July 5, 2025
BKTC’s Vikram Rawat Among 7 Killed In U’khand Helicopter Crash Near Kedarnath | India News
National

BKTC’s Vikram Rawat Among 7 Killed In U’khand Helicopter Crash Near Kedarnath | India News

June 15, 2025
The Third Eye: Envisioning India’s National Security Policy | India News
National

The Third Eye: Envisioning India’s National Security Policy | India News

June 15, 2025
Next Post
Is Cyclone Tauktae an indication towards a new trend for Arabian Sea?

Is Cyclone Tauktae an indication towards a new trend for Arabian Sea?

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

RECOMMENDED NEWS

What is the Wagner Group? Russian mercenaries on secret mission to kill Ukraine President Zelenskyy | World News

What is the Wagner Group? Russian mercenaries on secret mission to kill Ukraine President Zelenskyy | World News

3 years ago
Oil nears $100: Petrol, diesel price hike coming after elections

Oil nears $100: Petrol, diesel price hike coming after elections

3 years ago
Novak Djokovic flies out of Australia after losing court appeal | Tennis News

Novak Djokovic flies out of Australia after losing court appeal | Tennis News

3 years ago
UPSC Recruitment 2021: Apply for these Assistant Professor Posts, check the last date | India News

UPSC Recruitment 2021: Apply for these Assistant Professor Posts, check the last date | India News

4 years ago

BROWSE BY CATEGORIES

  • Animals
  • Architecture
  • Automobiles
  • Business
  • Culture
  • Fitness
  • International
  • Lifestyle
  • Movies
  • National
  • Sports
  • Technology
  • Travel

BROWSE BY TOPICS

Architecture culture Fitness indian architecture indian culture indian culture and heritage indian news lifestyle national news Technology technology news Travel travelling

About Us

Awaj Ludhiana Ki

Address

2667/3, Kishore Nagar, Tajpur & Jail Road, Ludhiana – 141008

Recent News

  • RTI Reveals Spy Suspect Jyoti Malhotra Was Kerala Govts State Guest; Custody Extended Till July 21
  • India Abstains From UN Resolution On Afghanistan, Calls For Efforts To End Exploitation Of Afghan Soil For Terrorism | India News
  • Indian Travellers With U.S. Visas Can Now Enter 17 Countries Without A Visa – Here’s The Full List | World News
  • From Slave To Superpower – How The U.S. Rose From British Colony To Global Warlord
  • UK F-35B Jet Under Repair In Kerala, UK Grateful To India For Support

Category

  • Animals
  • Architecture
  • Automobiles
  • Business
  • Culture
  • Fitness
  • International
  • Lifestyle
  • Movies
  • National
  • Sports
  • Technology
  • Travel

Search

No Result
View All Result

Email

[email protected]

  • About
  • Advertise
  • Careers

Copyright © 2019 Awaj Ludhiana Ki or it's affiliates | Website by Awaj Ludhiana Ki Team

No Result
View All Result
  • Home
  • Contact us
  • Animals
  • Architecture
  • Automobiles
  • Business
  • Culture
  • Fashion
  • Fitness
  • Food
  • International
  • Lifestyle
  • Movies
  • National
  • Sports
  • Technology
  • Travel
  • Punjab

Copyright © 2019 Awaj Ludhiana Ki or it's affiliates | Website by Awaj Ludhiana Ki Team

Login to your account below

Forgotten Password?

Fill the forms bellow to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In